The site had provided support for adults in the community – with the emphasis on getting people into work or further study.
A spokesperson for City of Bristol College said the Filwood Broadway Centre was given back to the landlords, Knowle West Partnership, on 30 September.
The decision regarding the closure of its provision at the Filwood Broadway Centre had been “based on our future curriculum plans and the strategic direction of the college.”
She said: “We continuously review our curriculum to ensure it meets the needs of our local communities and with our South Bristol Skills Academy located on the doorstep of the Filwood Broadway Centre, it was decided to focus on the curriculum delivery at this centre.
“Here the community are able to choose from a variety of courses including catering, hairdressing, animal care management, floristry and horticulture to name just a few. The college also delivers courses at further three centres (College Green, Ashley Down and Parkway), giving students an even wider choice of study options.”